Female Hormone Test (Comprehensive) (Saliva or Blood)

Hormones Tested
The Comprehensive Female Hormone Test is a safe and reliable lab test that uses a simple either blood serum or a saliva sample to measure your levels of Estrogen ( all three types: estradiol, estrone, estriol), Progesterone, Testosterone, and DHEA which are vital to a woman’s hormonal balance.
Reasons to take this test:
Menopausal and Perimenopausal Symptoms, Stress, Fatigue, Moodiness, Insomnia, Memory Weakness, Decreased Sexual Desire, Decreased Sexual Stimulation, Thinning and Loss of Pubic Hair, and Hormone Replacement Therapy (HRT) Monitoring.


Hormones exert a powerful influence over a woman’s health. Estrogens protect a woman from cardiovascular disease and osteoporosis and are vital for fertility. Progesterone levels affect mood, and balance the tissue proliferative effect of Estrogen. Testosterone increases energy, libido, and muscle.

A comprehensive assessment of your hormonal balance can be made by measuring Estrone, Estradiol, Estriol, DHEA, Progesterone, and Testosterone. Informed decisions regarding the need to initiate Bio-Identical Hormone Replacement Therapy (BHRT), or how to individualize therapy can then be made to maximize the health benefits of BHRT. Individual differences in hormone metabolism make monitored therapy the best choice for long term health.
Careful monitoring and individualization of BHRT can provide women with the benefits of supplemented natural Estrogen while reducing the risk of uterine, ovarian and breast cancer. (An increased cancer risk has been associated with conjugated Estrogen or synthetically modified hormone use. This is not the case with bio-identical or natural hormone use.)

A woman’s body produces three different Estrogens, in addition to DHEA, Progesterone and Testosterone which all start from cholesterol produced in the liver. Many women do not know that Testosterone is produced by both men and women. In fact, the steroid hormone Androstenedione is converted in both men and women to Testosterone first, then Testosterone is converted into Estradiol(E2), the major Estrogen secreted by the human ovary. The next most potent Estrogen is Estrone (E1), comes from Androstenedione. The third Estrogen, Estriol (E3), is synthesized outside the ovary in the peripheral tissues of the body from Estrone and Estradiol. It is known as the safe Estrogen.Estriol has been shown to be protective against Breast Cancer. Low levels of Estriol place you at an increased risk for developing cancer. You should check all of your Estrogen levels annually to make sure that they are in a healthy balance approximately equal to a ratio of at least 8:1:1, Estriol to Estrone to Estradiol, respectively. 

With advancing age, a woman’s ovarian function declines, leading to a decline in the production of Estrogen. This decline leads to vasomotor instability that causes hot flashes. It also causes decreased muscle mass, which is then replaced by fibrous tissue. Thinning skin is due to a loss of connective tissue support and elasticity. Vaginal mucous membranes also become thin and dry and breast tissue begins to sag. Supplementing natural Estriol (E3) can help stop many of these undesirable effects associated with menopause.
Progesterone is also produced by the ovaries from cholesterol. It has its own unique hormonal functions, but a certain amount is also converted into Estrogen. Progesterone increases uterine secretions and stimulates calcium deposits into bone tissue. It also helps regulate salt, control blood sugar, calms the nervous system and promote a healthy thymus gland. Supplementing natural Progesterone can help maintain these healthful benefits. You should have approximately ten times more Progesterone than Estriol for optimal balance.
When a woman’s ovarian function declines in the years before and during natural menopause, so does the amount of Testosterone she produces. Between a woman’s 20s and 40s the amount of Testosterone circulating in her blood declines about 50%. If a woman starts synthetic Estrogen Replacement Therapy at menopause, her blood levels of Testosterone drop even further due to a biochemical reaction.

Symptoms such as fatigue, muscle wasting, low sex drive, decreased sexual stimulation, and diminished sense of well-being can be due to a Testosterone deficiency. These symptoms may be significantly improved with natural Testosterone replacement.
DHEA is the most abundant steroid in the body. DHEA is a steroid precursor produced by the adrenal gland and converted to Testosterone and the Estrogens. DHEA levels decrease dramatically with age. Adequate DHEA levels give the body the building blocks necessary to produce these hormones. Low levels of DHEA are associated with and increase in coronary artery disease, muscle wasting, abdominal fat and osteoporosis. Taking DHEA reverses these processes and may also increase the sense of well-being.

Hormone levels affect health and well-being.
Monitoring hormone therapy increases therapy benefits while reducing side effects.
Due to individual differences in hormone absorption and metabolism, the hormone dosage required to attain physiologic levels will vary by patient and method of administration.


  1. Samsioe G. The endometrium: effects of estrogen and estrogen-progestogen replacement therapy. Int J Fertil Menopausal Stud 1994;39 Suppl 2:84-92
  2. Davis S. Androgen replacement in women: a commentary. J Clin Endocrinol Metab 1999 Jun;84(6):1886-91
  3. Watts NB. Hulka BS. Epidemilogical analysis of breast and gynecological cancers. Prog Clin Biol Res. 1997;396:17-29.
  4. Rosano GM, Panina G. Cardiovascular pharmacology of hormone replacement therapy. Drugs Aging 1999 Sep;15(3):219-34


Share on facebook
Share on twitter
Share on linkedin
Dr Hansen, Hansen Clinic of Natural Medicine

About the Author

Dr. Clark H. Hansen is a licensed Naturopathic Medical Doctor (N.M.D.) who has been in private practice in Scottsdale, Arizona, since 1986. He is the President and Medical Director of the Hansen Clinic of Natural Medicine, Aesthetics and Mesotherapy. Dr. Hansen is one of the most well respected Naturopathic Physicians in the country and a Diplomat of the World Society of Anti-Aging Medicine.

Subscribe for Updates