Individual Hormones Tested:
Pregnenolone (P) ($157.50)
Estrone (E1) ($150.93)
Estradiol (E2) ($185.74)
Progesterone (P4) ($139.59)
Dehydroepiandrosterone (DHEA) ($153.41)
Testosterone (T) (195.50)
DiHydroTestosterone (DHT) ($130.31)
Sex Hormone Binding Globulin (SHBG) ($150.00)
Free Testosterone (FT) ($25.00)
List Price: $1285.00
Hansen Clinic 9 Panel Price:
$850 Sale Price $425
Andropause, or male hormone decline, affects millions of U.S. adult males. Testosterone levels in men begin dropping after age 30 but the changes are gradual until the level drops below 400-500ng/dl. In men, a total Testosterone level below 300 ng/dl, measured on two separate occasions, is generally considered diagnostic for low Testosterone, however, optimal Testosterone levels range between 800-1200ng/dl. According to the American Association of Clinical Endocrinologists, low levels of testosterone in men are associated with muscle loss, aches and pains, low sex drive, increased belly fat, Obesity, Type 2 Diabetes, Metabolic Syndrome and an increased incidence of Cardiovascular Disease, including heart attacks. In fact, low Testosterone concentrations have been shown to be predictive of an increase in death from all causes, especially in men >70 years of age. Men can greatly reduce their risks of disease and restore their youthful vitality by taking Bioidentical Hormone Replacement Therapy, including Testosterone.
The Hansen Clinic Male 9 Hormone Panel Blood test is a safe and reliable lab test that uses specialized laboratory facilities to obtain the most accurate and consistent lab results. Most doctors do not order these tests and so most labs have not invested the time or money to develop accurate and consistent hormone testing. The 9 key hormone levels that should be tested include Pregnenolone, two Estrogens [Estrone (E1), Estradiol (E2), which can cause fatty breasts and Prostate Cancer if too high in men, Progesterone, DHEA., Testosterone, Dihydrotestosterone (DHT), Sex Hormone Binding Globulin (SHBG), and Free Testosterone. These hormones are all vital to a man’s hormonal balance, prevention and treatment of back pain, low energy, depression, elevated cholesterol, a decreased sex drive, Erectile Dysfunction, abdominal weight gain, Osteoporosis, Heart Disease and Cancer.
Hormones exert a powerful influence over a man’s health. DHEA regulates cortisol and thyroid hormones, lubricates your joints and helps make Testosterone. Testosterone increases energy, libido, muscle strength and confidence, bone density and prevents brain fog and plaque build-up in the arteries. Progesterone calms your mood, improves sleep, builds bone and activates Tumor Suppressor Protein, (p53) helping to prevent cancer.
A comprehensive assessment of your key hormone levels should be part of an annual check-up for men. For optimal health, men should be testing the following hormones annually: Pregnenolone, Estrone, Estradiol, DHEA, Progesterone, Testosterone,DHT, SHBG and Free Testosterone. With this information you can make Informed decisions regarding your need to initiate Bio-Identical Hormone Replacement Therapy (BHRT), or how to individualize therapy to maximize your health benefits using BHRT. Individual differences in hormone metabolism make monitored therapy the best way to prevent hormonal ancers and push back the signs of aging.
Careful monitoring and individualization of BHRT can provide men with the amazing benefits of Bioidentical Testosterone while reducing the risks of heart disease, diabetes, osteoporosis, dementia and Prostate Cancer.
Pregnenolone is the most highly concentrated hormone in the human brain. It is the key hormone that nourishes the brain and protects the nervous system. It is called the “Mother Hormone” because from it all of the other key hormones are derived. Pregnenolone is made in the brain and the adrenal glands from cholesterol and then converted in the liver to DHEA and Progesterone, which then are ultimately converted into all the other key hormones, including Cortisol, Testosterone and the three Estrogens. Beginning at age 35, the body’s natural Pregnenolone levels start to decline. By age 50 they are 50% reduced and by age of 75 the body’s production of this essential brain hormone is almost totally depleted. It’s no wonder we associate memory decline, dementia and Alzheimer’s disease with aging.
In addition to Pregnenolone, DHEA, Progesterone and Testosterone which all start from cholesterol produced in the liver, a man’s body produces three different Estrogens, just like a woman’s, albeit at a much lower dose.
You should check your hormone levels annually to make sure that they are in a healthy balance. Too much Estradiol that can increase your risk of Prostate Cancer. Balance is the essential key. You need to work closely with a doctor that understands all of the hormones and the intricate balance that must be kept in order to achieve optimal health.
Dihydrotestosterone is formed from Testosterone in specific tissues and is a more potent androgen than testosterone. Too much DHT, howerver, has been associated with causing Benign Prostate Hypertrophy (BPH), acne and baldness.
Progesterone is mostly produced by the ovaries in women starting from cholesterol. It has its own unique hormonal functions, but a certain amount may also be converted into Estrone. Progesterone increases uterine secretions and stimulates calcium deposits into bone tissue. It also helps regulate salt, control blood sugar, calms the nervous system and promote a healthy thymus gland. Progesterone also activates GABA, the anti-anxiety and deep sleep Neurohormone. Perhaps the most important function of Progesterone is the activation of an anti-cancer protein known as Tumor Suppressor Protein, or p53. Supplementing natural Progesterone can help maintain these healthful benefits. You should have approximately 10 times more Progesterone than Estriol and 100 times more Progesterone than Estradiol for optimal health. You should make sure to check your levels annually.
DHEA is the most abundant steroid in the body. DHEA is a steroid precursor produced by the adrenal gland and converted to Testosterone and the Estrogens. DHEA levels decrease dramatically with age. Adequate DHEA levels give the body the building blocks necessary to produce these hormones. Low levels of DHEA are associated with and increase in coronary artery disease, muscle wasting, abdominal fat and osteoporosis. Taking DHEA reverses these processes and may also increase the sense of well-being.
Testosterone is the pre-eminent male hormone, however, it is produced by both men and women. Low Testosterone causes symptoms of fatigue, muscle wasting, low sex drive, decreased sexual stimulation, and diminished sense of well-being. Low Testosterone also causes increased riks of dying from all causes, but particularly, heart disease. These can be significantly reduced with optimal levels of natural Testosterone replacement.
A review of the National Library of Medicine’s more than 9 million articles includes overwhelming evidence that Testosterone does NOT cause an increased incidence of Heart Disease, or Heart Attack. In fact the opposite is true. Researchers from the University of Florence, Italy, Sapienza, Rome, and Hospitals in Bologna and Florence, recently performed an updated systematic review and meta-analysis of all placebo-controlled randomized clinical trials (RCTs) on the effect of Testosterone Supplementation (TS) on Cardiovascular-related problems. (Expert Opin Drug Saf. 2014 Aug 19:1-25. [Epub ahead of print] Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis.
“Men with lower testosterone levels had an increased risk of dying from any cause, but most particularly of cardiovascular disease,” according to Dr. Kay-Tee Khaw. “We looked at cancer, too, and found no evidence of a link to cancer with higher testosterone levels. These finding comes from a study of British men aged 40 to 79 by University of Cambridge gerontologist Kay-Tee Khaw, MBBCh, and colleagues. (Khaw, K.-T. Circulation, Dec. 4, 2007; vol 116, manuscript received ahead of print. Kay-Tee Khaw, MBBCh, professor of clinical gerontology, University of Cambridge, England. Robert Davis, MD, professor of urology, University of Rochester, N.Y.)
Sex Hormone Binding Globulin
SHBG is a protein that binds testosterone and estradiol and transports them in the blood. As a result, the SHBG level affects the amount of these hormones that are available in the body.
SHBG has a high binding affinity to Dihydrotestosterone (DHT), medium affinity to Testosterone and Estradiol, and only a low affinity to Estrone, DHEA, Androstenedione, and Estriol. Elevated SHBG levels can be seen in men and women with high estrogen levels or hyperthyroidism (high thyroid levels) and significant liver disease. SHBG levels also increase when women take oral contraceptives or oral Hormone Replacement Therapy. Pregnant women also have markedly higher SHBG serum concentrations due to their increased estrogen production.
Free Testosterone (Bioavailable Testosterone)
Free Testosterone is the biologically active Testosterone. It provides the best representation of the true functioning level of active Testosterone in the blood stream and its effects on the patient. Free testosterone is also referred to as Bio-Available Testosterone, or the Non-SHBG-bound Testosterone. By calculating the Free Testosterone from the ratio of total testosterone (TT) to SHBG [% FT = (TT / SHBG) x 100], it is possible to calculate the approximate amount of Free Testosterone (FT) that is circulating in the blood stream and available to perform the healthy functions of Testosterone.
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- Rosano GM, Panina G. Cardiovascular pharmacology of hormone replacement therapy. Drugs Aging 1999 Sep;15(3):219-34
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