How to Balance Your Hormones to Prevent Cancer

The Key to Optimal Health is Balance

Excess Estrone & Estradiol

• PMS Breast tenderness
• Acne
• Migraines
• Endometriosis
• Polycystic Ovarian Syndrome
• Breast Cancer
• Uterine Cancer
• Ovarian Cancer

Get to Know Your Estrogens

The body makes three estrogens: Estrone (E1), Estradiol (E2) and Estriol (E3). These three hormones need to be kept in balance to prevent excessive proliferation of cells that could lead to breast, ovarian or uterine cancer. Estriol was overlooked and mostly ignored in the early days of estrogen research because it is 1000 times less concentrated than Estrone and Estradiol. For this reason it has all but been forgotten. 

The two most concentrated and most potent estrogens are Estrone (E1) and Estradiol (E2). They are the hormones that stimulate cell growth of the uterine lining and breast tissue associated with preparation for pregnancy. Because they stimulate cell growth, they can also stimulate cancer cell growth.

Both Estrone and Estradiol are now classified as carcinogens. A woman cannot make a baby without them, but too much can cause cancer, so nature gave women three hormones for balance. When a woman becomes pregnant, she stops making high levels of Estrone and Estradiol and starts making lots of Estriol. This increased balance of Estriol decreases cellular proliferation and reduces a woman’s risk of getting breast cancer by 7% for every pregnancy and 4% more for every baby she breast feeds for at least 12 months.

Estriol is the Key Estrogen in Pregnancy and Menopause

A low Estriol level puts you at risk for all the symptoms of Menopause. On the other hand, having an optimal level of Estriol stops hot flashes, vaginal dryness, painful intercourse, thinning of the skin, mental dullness and brain fog associated with Menopause and Peri-Menopause. Making sure you have optimal levels of Estriol can also protect you from getting breast cancer. Estriol is the Safe/Protective Estrogen. It has been shown to protect the breasts from developing cancer and the nervous system from Multiple Sclerosis and other autoimmune diseases.

Estriol (E3) is the Safe / Protective Estrogen

Estriol (E3) is the “safe / protective estrogen” Because it selectively binds to estrogen receptor-beta (ER-beta), which inhibits breast cell proliferation and prevents breast cancer development. (Source: Postgraduate medicine, Vol 121, Issue 1, January 2009; Endocrinology. 2006 Sep;147(9):4132-50. Epub 2006 May 25.) Estrone and Estradiol, on the other hand, stimulate estrogen receptor-alpha (ER-alpha), which activates breast cell proliferation and increases a woman’s risk of cancer.

Taking supplemental Estriol (E3) produces a 30% reduced risk of breast cancer, while Estradiol (E2) alone causes a 10% increased risk of breast cancer. (Source: Fournier et al, “Breast cancer risk in relation to different types of hormone replacement therapy in the E3N-EPIC cohort,” Int J Cancer 2005 Apr 10;114(3):448-54.)

Additionally, too much Estradiol (E2) increases a woman’s risk of cancer by activating a protein known as bcl-2, which promotes cancer cell growth and decreases Tumor Suppressor Protein (known as p53), which is one of the body’s primary cancer prevention mechanisms. Again the key is optimal balance. (Source: Ann Clin Lab Sci. 1998 Nov-Dec;28(6):360-9; Int J Cancer. 2003 Jul 10;105(5):607-12)

What is the Optimal Estrogen Balance?

The third Estrogen, Estriol (E3), is made by nature to balance the other two. It prevents excessive cell proliferation that leads to cancer. Estriol is made outside the ovary in the peripheral tissues of the body. It is the safe / protective Estrogen.

Estriol provides all the health benefits of its sister estrogens, but does not cause the excessive build up of breast cells or the uterine lining that is associated with breast and uterine cancer. In fact, research indicates that low levels of Estriol place you at an increased risk for developing cancer. You should check all of your Estrogen levels annually to make sure that they are in optimal balance. A woman should have at least ten times (10x) more Estriol than Estrone or Estradiol. And your Prgesterone level should be one hundred times (100x) higher than your Estradiol level. To learn more aboutthe power of Progesterone for women and men, click here

Synthetic Hormone Replacement Therapy (HRT)

vs Bio-Identical Hormone Replacement Therapy (BHRT)

Drug manufacturers have been making synthetic estrogen drugs for more than 50 years to combat these changes. However, in July 2002, researchers at the National Institutes of Health abruptly halted the nation’s largest study on HRT, because the study found that the long-term use of synthetic estrogen and synthetic progesterone drugs increase a women’s risk of breast cancer by 26%, her risk of a heart attack by 29%, her risk of stroke by 41% and her risk of blood clots by 113%. (Source: JAMA. 2002;288:321-333).

In spite of the warnings of this study many women are feeling conflicted and even deserted without being healthy alternatives . Many women are being told to take anti anxiety or anti-depresant medicaations instead of HRT. Approximately thdree million women who abruptly stopped the Premarin or PremPro have gone back to taking the HRT because they cannot endure the hot flashes, night sweats and sleepless nights. The abrut stopping of their hormones also caused the return of  brainfog, anxiety, depression and emotinal instability, and they fear the coming thinning of their skin, ones and vaginal membranes, painful intercourse and otherr signs of aging asssociated decline of their hormones. They were told that Hormone Replacement Therapy was an indefinite postponement of aging and that hope has now suddenly disappeared in the face of the real possiblitly of Cancer.

Estriol & Progesterone are Made by Nature to Reverese the Risks 

Unfortunately, millions of women have never heard the good news that there are safe and effective natural bio-identical hormones that can provide relief without the risk of Cancer. Infact natural bio-identical Estriol (E3) and Progesterone were made by Nature to counter balance Estrone(1) and Estradiol(E2), which should decline after the child bearing years are over to prevent cancer risk.

Estriol and Progesterone are essential bio-identical hormones, which the body produces to offset the potential risks that would otherwise be caused by Estradiol and Estrone. They block the overproduction of these hormones and specifically counterbalance their effects by doing the exact opposite of Estrone and Estradiol. Estriol activates the opposing Estrogen Receptor, known as ER-beta. Estrone and Estradiol stimulate ER-alpha, which causes cellular prolferation and cancer. ER-beta revereses cellular proliferation. Progesterone decreases bcl-2 (another protein that increases cellular proliferation and the risk of cancer of the breasts, uterus and ovaries). Progesterone also increases Tumor Suppressor Protein (p53), which activates DNA repair and initiates cellular apoptosis, which is the programmed death of cells that have become cancerous due to DNA damage that is irreparable.

What’s more, synthetic estrogens and progestins, such as Premarin, Estrace, Beta-Estradiol and PremPro, etc, cause even more damage because they amplify the adverse hormonal imbalance by over expressisng a protein known as MDM2 that blocks the production of Tumor Suppressor Protein (p53) that is naturally activated by Progesterone.

In February, 2009, a study published in the New England Journal of Medicine, found that women who take synthetic estrogen-progestin combination hormone therapy for more than five years suffer a doubling of their risk of getting breast cancer and worse yet, the risk doubles again every additional twelve months they continue to take the synthetic hormones rather than the natural, bio-identical hormones. (N Engl J Med. 2009 Feb 5;360(6):573-87)

So,  why do doctors not tell women about these natural bio-identical alternatives? The answer is stunning and sad, but true. Doctors can only prescribe the syntheti pharmaceutical drugs listed in the drug formulary mandated by the medical complex that employs them. And why don’t the drug companies make and provide the natural bioi-idential alternatives? Unfortunately, it is because they can’t patent a natural bio-identical hormone, because God holds the patent to all things natural. In order to get the exclusivity that a patent provides an the huge monetary income that it generates, they copy the natural substance  and then change it just enough tocall it unique and exclusive so that they can get the patent. And the deletions or additions are the reasons that the drugs then cause so many serious side-efects.

So What Does Dr. Hansen’s Rx?

I always reommend what God has given us first. Do the things that stimulate your innate healing from within and then supplement deficiencies with natural bio-identical alternatives made by nature, which was made by God.

Start by testing your hormones and keep them in Balance!

1) Progesterone: Should be 100 x higher than Estradiol (E2)

[Progesterone activates Tumor Suppressor Protein (p53)]

2) Estriol: Should be 10 x higher than Estradiol (E2)

Estriol Stimulates ER-beta, which inhibits breast cell proliferation and cancer

3) Estrone (E1) and Estradiol (E2) should be kept in Low Range

E1 and E2 are known carcinogens that cause Invasive Breast Cancer AND they are

amplified 10x when combined with Progestins (Oral Contraceptives and synthetic HRT)

This is more effective than getting a Mammogram for the prevention of Breast Cancer. Take 10 times more Estriol (E3) than Estradiol (E2) and 100 times more Progesterone than Estradiol (E2). Makesure our Estrone and Estradiol are within in optimal range and don’t forget Testosterone. The Testosterone story will have to wait for another day, but you need to make sure you have enough. It is essential for women too. It will prevent heart disease, give you strengthe and burn fat, prevent diabetes and dementia and it will increase your mood energy and sexual sensitivity. Find out more in my next Vital Health Newsletter.