Micro-needling: The New Anti-Aging Breakthrough

by Dr. Clark Hansen, NMD | Sep 2, 2015

Micro-needling: The Newest, Most sought afterÂ Skin Rejuvenating Therapy

The Micropen is a medical grade, state-of-the-art Micro-needling Pen designed to reverse years of skin wrinkling, sun damage, hyper-pigmentation, acne scarring, stretch marks, and thinning skin and thinnning scalp hair. The Micropen’s 12 enclosed medical grade micro needles create hundredsÂ of tiny micro-channels through the epidermis into the deeper dermis. This controlled micro-needling triggers the natural process of collagen and elastin regeneration and repair without scaring and results in improvedÂ skin resiliency, strength, thickness, hydration and smoothness, producingÂ healthier, more youthful looking skin.Â Micro-needling activates the bodyâ€™s ability to remodel and regenerate itself with amazing benefits and no downtime.

Â The Causes of Aging Skin and Connective Tissue

As we age, radiation fromÂ the sun, environmentalÂ chemicals and declining production of Growth Hormone leading to a decline in Collagen and Elastin production, leadsÂ to oxidative damage to the skin and inability to repair fast enough to keep up with the damage. Rapid changes begin to occur in our 30’s. The skin takes twice as long to regenerate as it did in our 20’s, which leads to a dull complexion, uneven skin tone and fine lines and wrinkles. In our 40’s, Collagen and elastin production declines and degradation speeds up, leading to the first appearance of deeper wrinkles and loss of elasticity, suppleness and resiliency. Â In our 50’s and beyond, environmental damage continues to mount, while declining Growth Hormone andÂ Estrogen lead to thinning of the skin and the subcutaneous tissue. The skin becomes more susceptible to photo aging and the appearance of ageÂ spots, sagging and wrinkled skin.

Signs of Skin Aging Reversed by Micro-needling

Lax Skin / Loss of Resiliency
Hyperpigmentation / Age Spots
Thin skin
Wrinkles
Premature Aging / Glycation
Acne Scars
Stretch Marks
Hair Loss

Micro-needling Before and After Photos

Benefits of Micro-needling

Normalizatoin of cell-to-cell communication
Faster Tissue Repair and Regeneration
Restoration of HealthyÂ Keratin and Melanocyte function
Optimizes Normal Pigment / Skin Coloration
Increases Epidermal and Dermal Growth Factors
Stimulation of Healthy New Collagen & Elastin
Enhances Delivery of Cellular Nutrients
Faster healing of inflammation and oxidation
Remodels scarring and stretch marks with healthy Collagen & Elastin
Stimulation ofÂ Circulation &Â Growth Factors required for Hair Growth

Advanced Micro-needling Pens

The Micro-needling Pen’s Advanced Medical Features Include:

Patented high speed motor with accurate speed and power control to assure correct depth of penetration.
The variable depth (.25mm to 2.0mm) and speed of Microen provides significant versatility to remodel the skin in many areas of the body, including the face, neck, declotet, arms, hands, legs, abdomen, back and even the scalp. The procedure takes 30-45 minutes for a typical treatment of the face and requires no downtime.
Patented single use, sterile Micropen cartilage technology prevents cross-contamination, which allows you to receive a Micro-needling treatment confident that no fluids, serums and blood generated during a previous procedure remain in the device.
Automated, vertically vibrating, stamp-like needle cartridge prevent scratching the epidermis.
12 sterile, 32-gauge needles made of medical grade stainless steel minimize epidermal damage and maximize results.
The Microen is safer and more precise in piercing the skin than other Micro-needling Pens or Rollers.

Precise micro-channels created by the 12 Microen Micro-needles deliver therapeutic serums directly to the deeper layers of the skin where they can stimulate collagen and elastin that can only be made there.
Micropen’s small round stamp-like shape and size can effectively treat hard-to-reach places (e.g. around the eyes, nose, and lips).
Because of the accurate 90 degree delivery, the 12 precisely placed needles can easily penetrate the epidermis to promote scar-less healing and natural collagen production, similar to fractional laser treatments, but without the side effects and downtime.
The mechanism of injury is a natural process, which makes Micropen a holistic approach to skin therapy.

How Micro-needling Works

Four major phases of natural dermal and epidermal wound healing resultsÂ in the enhanced stimulation of new healthy skin.
Phase One (Days 1-3) | Inflammation:Â Activated by piercing the dermal tissue, platelets release cytokines and growth factors which act as signals for the body’s immune system. White blood cells (Neutrophils and Macrophages) are sent in to disinfect the wounds, clear the debris, increase the blood supply (a process called angiogenesis), and begin the creation of fresh, new skin (1-3 days).

Phase Two (Days 3-5) | Proliferation:Â In this phase, the fibroblasts (cells that make up much of the dermis and create the extracellular matrix) keratinocytes and epidermal cells continue to divide to populate the areas of damage and secrete growth factors and extracellular matrix, such as elastin and collagenÂ will be laid down and deposited with new tissue formation. Phase
Three (Days 6-30) | Remodeling:Â Â During this phase, Collagen and Elastin producing Fibroblasts proliferate in the puncture wounds formed by the micro-needles and migrate, with the help of Growth Factors and Fibronectin. The collagen in the newly formed tissue is now replaced with even stronger collagen and the dermisÂ contracts to create a youthful firm, but suppleÂ texture to the skin.
Phase FourÂ (Months 2-12) | Maturation:Â Finally, the maturation stage of new healthy skin takes place from day 28 to two years after treatment. Collagen matures and creates an organized cross-linking meshwork that is oriented along the lines of contour stress to provide optimal support, strength and supple resiliency to the skin.

Micro-needling: Is it Right For You?

Amazing results, nearly painless, fast, minimal down-time and long-lasting way to get rid of your wrinkles. Also known asÂ Collagen Induction Therapy (CIT), Micro-needling dramaticallyÂ increases the amount of healthy collagen or elastin in the skin.Â The micro-channels created by the Micro-needling allow for infusionÂ of plasmaÂ and serum Growth Factors to rejuvenate the skin for long lasting functional changes that reduce fine lines and deep wrinkles, hyper pigmentation, age spots,Â acne scars, stretch marks andÂ leads to improved volume, strength, resiliency, smoother texture and a brighter complexion to create healthier more youthful looking skin.
For More Information or a FREE Consultation to learn what Micro-needling Therapy can do for you, please call us today at 480-991-5092. Dr. Hansen and his wife, Sheila, who is a Licensed Aesthetician,Â will be happy to discuss your individualÂ skin conditions and goals.

Pricing:

Micro-needling with Hyaluronic Acid: $395; with Anti-Aging Peptide Serum: $495, or with Platelet Rich Plasma (PRP) $595.

Ivermectin + Mebendazole taken together produce remarkably Positive Clinical Cancer Benefits in 84.4% of Patients.

The largest real-world human analysis to date evaluating ivermectin and mebendazole in cancer patients has just been published—and the results represent one of the most compelling clinical signals ever documented for repurposed anti-parasitic therapies in oncology.

This groundbreaking analysis was made possible through a unique collaboration between The Wellness Company, the McCullough Foundation, and the Chairman of the President’s Cancer Panel (Dr. Harvey Risch)—uniting real-world clinical data, frontline medical experience, and high-level epidemiologic expertise to deliver urgently needed insights in oncology.

This was a real-world prospective clinical program evaluation of 197 cancer patients, with 122 completing a follow-up survey at about six months (61.9% response rate).

Cancer patients were prescribed compounded ivermectin–mebendazole, with each capsule containing 25 mg ivermectin and 250 mg mebendazole—most commonly taken at 1–2 capsules per day.

The cohort represented a clinically relevant population, including a wide variety cancer types, with 37.1% of patients reporting actively progressing disease at baseline and many having already undergone chemotherapy, radiation, and surgery.

At six months, 84.4% of cancer patients reported clinical benefit (Clinical Benefit Ratio: 84.4% [95% CI: 77.0–89.8%]):

✅ 32.8% reported NO evidence of cancer (95% CI: 25.1–41.5%)
✅ 15.6% reported tumor regression (95% CI: 10.2–23.0%)
✅ 36.1% reported stable disease (95% CI: 28.1–44.9%)

Treatment adherence was high, with 86.9% completing the full protocol and 66.4% remaining on therapy at six months.

The regimen was well tolerated, with 25.4% reporting side effects, primarily mild and gastrointestinal, and over 93% continuing treatment despite these events.

Patients were treated in real-world conditions alongside concurrent therapies, including chemotherapy (27.9%), radiation (21.3%), surgery (19.7%), supplements (49.2%), and dietary modification (37.7%), supporting use as an adjunctive approach.

Together, these findings represent a large, internally consistent real-world clinical signal that supports URGENT further investigation of ivermectin and mebendazole as low-toxicity, adjunctive cancer therapies.

Given the strength of the signal observed here, advancing this line of investigation is no longer optional—it is necessary.

This is NOT the end. We will continue advancing this work with larger datasets to further define and validate the role of anti-parasitics in cancer outcomes.

The manuscript is now available as a preprint on the Zenodo research repository, operated by the European Organization for Nuclear Research, while undergoing peer review at leading oncology journals: “Real-World Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort.”

Click Here to see the full Report of the Research